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Steve E Humphries Selected Research

Coronary Disease (Coronary Heart Disease)

1/2021Genetic testing for familial hypercholesterolemia-past, present, and future.
1/2020Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274.
1/2019Polygenic Hypercholesterolemia and Cardiovascular Disease Risk.
6/2017Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.
3/2017The UK Paediatric Familial Hypercholesterolaemia Register: preliminary data.
1/2017Genetic Architecture of Familial Hypercholesterolaemia.
1/2017Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene.
1/2017PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
10/2016Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies.
4/2016Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.
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Steve E Humphries Research Topics

Disease

67Coronary Disease (Coronary Heart Disease)
01/2021 - 04/2002
31Type 2 Diabetes Mellitus (MODY)
01/2021 - 04/2003
30Atherosclerosis
12/2021 - 03/2002
30Coronary Artery Disease (Coronary Atherosclerosis)
10/2019 - 03/2002
29Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 02/2002
24Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
01/2022 - 09/2004
17Inflammation (Inflammations)
01/2020 - 03/2002
11Myocardial Infarction
05/2012 - 06/2003
9Stroke (Strokes)
06/2017 - 04/2005
9Hypertension (High Blood Pressure)
01/2017 - 02/2002
8Insulin Resistance
10/2016 - 06/2004
7Atherosclerotic Plaque (Atheroma)
01/2020 - 11/2004
7Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2017 - 04/2003
6Ischemic Stroke
10/2019 - 09/2004
6Obesity
01/2018 - 06/2004
6Abdominal Aortic Aneurysm
01/2018 - 07/2010
5Genetic Risk Score
05/2020 - 01/2015
5Diabetes Mellitus
01/2017 - 02/2006
4Hypercholesterolemia
05/2020 - 07/2002
4Heart Diseases (Heart Disease)
08/2016 - 03/2006
4Carotid Artery Diseases
03/2015 - 08/2003
3Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
06/2017 - 01/2002
3Necrosis
04/2017 - 06/2003
3Xanthomatosis (Xanthoma)
08/2014 - 03/2006
3Dyslipidemias (Dyslipidemia)
06/2011 - 01/2005
3Myocardial Ischemia (Ischemic Heart Diseases)
04/2004 - 03/2002
2Hyperplasia
01/2020 - 01/2016
2Muscular Diseases (Myopathy)
11/2019 - 02/2013
2Body Weight (Weight, Body)
12/2015 - 01/2015
2Pancreatitis
01/2015 - 08/2014
2Periodontitis
04/2014 - 04/2005
2Rheumatoid Arthritis
05/2013 - 03/2012
2Thrombosis (Thrombus)
08/2012 - 03/2003
2Vascular Diseases (Vascular Disease)
08/2012 - 09/2003
2Venous Thrombosis (Deep-Vein Thrombosis)
10/2011 - 04/2004
2Respiratory Insufficiency (Respiratory Failure)
12/2008 - 09/2002

Drug/Important Bio-Agent (IBA)

41LipidsIBA
01/2021 - 04/2002
23LDL CholesterolIBA
01/2022 - 09/2004
21Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2020 - 05/2003
21Interleukin-6 (Interleukin 6)IBA
01/2020 - 04/2002
21CholesterolIBA
11/2019 - 07/2002
19oxidized low density lipoproteinIBA
01/2021 - 08/2007
19Triglycerides (Triacylglycerol)IBA
01/2021 - 11/2002
17Biomarkers (Surrogate Marker)IBA
04/2017 - 06/2005
11Apolipoproteins E (ApoE)IBA
01/2021 - 04/2004
11CytokinesIBA
10/2019 - 06/2003
10HDL CholesterolIBA
01/2020 - 02/2003
9ApolipoproteinsIBA
01/2017 - 04/2002
9Glucose (Dextrose)FDA LinkGeneric
01/2017 - 02/2002
9Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
12/2008 - 01/2002
8LDL Receptors (LDL Receptor)IBA
01/2021 - 11/2007
8Apolipoproteins B (ApoB)IBA
01/2021 - 11/2002
8DNA (Deoxyribonucleic Acid)IBA
11/2019 - 03/2006
8Insulin (Novolin)FDA Link
11/2017 - 04/2003
8Lipoproteins (Lipoprotein)IBA
08/2014 - 04/2004
7Pharmaceutical PreparationsIBA
10/2019 - 07/2002
7Proteins (Proteins, Gene)FDA Link
04/2017 - 03/2004
6InterleukinsIBA
04/2017 - 04/2002
6C-Reactive ProteinIBA
10/2011 - 08/2008
5Secretory Phospholipases A2IBA
04/2015 - 01/2006
4Interleukin-18 (Interleukin 18)IBA
04/2017 - 05/2007
4HDL LipoproteinsIBA
01/2017 - 06/2005
4AntioxidantsIBA
08/2016 - 03/2004
4Biological ProductsIBA
04/2014 - 06/2005
4Lipoprotein Lipase (Diacylglycerol Lipase)IBA
10/2010 - 02/2003
4Gemfibrozil (Lopid)FDA LinkGeneric
04/2004 - 03/2002
3CreatinineIBA
11/2019 - 09/2008
3ORALIT (ORS)IBA
10/2019 - 10/2009
3SubtilisinIBA
01/2017 - 12/2007
3AdiponectinIBA
08/2015 - 05/2009
3Vitamin DFDA LinkGeneric
01/2015 - 11/2013
3Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
01/2015 - 03/2012
3hydroxide ionIBA
09/2014 - 11/2013
325-hydroxyvitamin DIBA
09/2014 - 11/2013
3LDL Lipoproteins (beta Lipoproteins)IBA
07/2014 - 09/2010
3EnzymesIBA
04/2014 - 10/2002
3Phospholipases (Phospholipase)IBA
11/2013 - 01/2006
3Fibrinogen (Factor I)FDA Link
04/2012 - 04/2005
3Aryldialkylphosphatase (Paraoxonase)IBA
01/2012 - 04/2002
3HomocysteineIBA
08/2011 - 02/2004
3Angiotensin IIIBA
12/2007 - 10/2003
3Lipase (Acid Lipase)FDA Link
06/2005 - 04/2004
3PPAR alphaIBA
02/2005 - 02/2002
2Lipoprotein(a)IBA
01/2022 - 08/2012
2Peptide Hydrolases (Proteases)FDA Link
01/2020 - 11/2004
2Matrix Metalloproteinases (MMPs)IBA
01/2020 - 10/2013
2PCSK9 InhibitorsIBA
01/2019 - 01/2017
2ProinsulinIBA
11/2017 - 06/2003
2Blood Proteins (Serum Proteins)IBA
04/2017 - 10/2011
2Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
01/2017 - 06/2013
2Interleukin-5 (Interleukin 5)IBA
05/2016 - 03/2015
2Messenger RNA (mRNA)IBA
03/2016 - 04/2014
2ReninIBA
01/2015 - 10/2003
2Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA
07/2014 - 06/2005
2IsoenzymesIBA
04/2014 - 11/2013
2Apolipoprotein B-100 (Apo B 100)IBA
01/2014 - 09/2004
2Peptides (Polypeptides)IBA
01/2014 - 05/2013
2Cholesterol Ester Transfer ProteinsIBA
01/2012 - 10/2008
2Acute-Phase Proteins (Acute-Phase Protein)IBA
02/2009 - 06/2003

Therapy/Procedure

11Therapeutics
11/2019 - 10/2003